Expression of HP1 and ZNF genes in lamin A/C knock-down clones.

<p>Values indicate fold-change in real-time PCR transcripts (upregulation) expressed as mean ± SD calculated from three independent experiments for two stable HeLa clones, Cl 26 and 27 expressing lamin A/C shRNA, compared to a stable clone expressing the control vector.</p>*<p><i>p</i>≤0.05,</p>**<p><i>p</i>≤0.01. Cl 26 and 27 showed 2- and 5-fold reduction in lamin A/C transcripts respectively and ∼90% depletion of lamin A/C protein [ref 20].