<p>(A) A scheme of the MAPK pathway. (B) Mapping the mutations onto the three dimensional structures; mutations located at or close to the active site are colored in blue, otherwise colored in red.</p
Mitogen-activated protein kinases 1 and 3 (MAPK1 and MAPK3), also called extracellular regulated kin...
For each subject, genotypes of all analyzed variants are shown on a row of three heatmaps that are b...
<p>Protein chains under parallel evolution are denoted in light blue, their functional domains are d...
<p>(A) The reduced model; (B) the reduced model with initial conditions from Fujioka et al; (C) the ...
<p>A) Localization of mutated residues in the closed conformation of GK. A to E) An enlargement of t...
<p>Note: red tags showed the up-regulated genes, green tags showed the down-regulated genes.</p
The decreasing cost of genome sequencing technology has lead to an explosion of information about wh...
The decreasing cost of genome sequencing technology has lead to an explosion of information about wh...
Homology model of scFv mutants 1, 2, 7, 8 and 15 from table number 3 are shown as A, B, C, D and E r...
<p>(A) The SF162 V2 wildtype sequence and a list of the mutations that were introduced at 13 differe...
<p>(A) Mutations observed in AML (pink spheres) that show resistance to quizartinib are mapped onto ...
<p>A–C) Representative images of phospho-Thr172-AMPK (red) localization in mitotic cells from wild-t...
abstract: Pantothenate kinase-associated neurodegeneration, PKAN, is a neurological disease that is ...
Musalula Sinkala et al. report that collectively, specific mutations of genes in 5 MAPK pathways are...
<p>One non-synonymous mutation (Ile > Met) was identified.(A) The three-dimensional model before mut...
Mitogen-activated protein kinases 1 and 3 (MAPK1 and MAPK3), also called extracellular regulated kin...
For each subject, genotypes of all analyzed variants are shown on a row of three heatmaps that are b...
<p>Protein chains under parallel evolution are denoted in light blue, their functional domains are d...
<p>(A) The reduced model; (B) the reduced model with initial conditions from Fujioka et al; (C) the ...
<p>A) Localization of mutated residues in the closed conformation of GK. A to E) An enlargement of t...
<p>Note: red tags showed the up-regulated genes, green tags showed the down-regulated genes.</p
The decreasing cost of genome sequencing technology has lead to an explosion of information about wh...
The decreasing cost of genome sequencing technology has lead to an explosion of information about wh...
Homology model of scFv mutants 1, 2, 7, 8 and 15 from table number 3 are shown as A, B, C, D and E r...
<p>(A) The SF162 V2 wildtype sequence and a list of the mutations that were introduced at 13 differe...
<p>(A) Mutations observed in AML (pink spheres) that show resistance to quizartinib are mapped onto ...
<p>A–C) Representative images of phospho-Thr172-AMPK (red) localization in mitotic cells from wild-t...
abstract: Pantothenate kinase-associated neurodegeneration, PKAN, is a neurological disease that is ...
Musalula Sinkala et al. report that collectively, specific mutations of genes in 5 MAPK pathways are...
<p>One non-synonymous mutation (Ile > Met) was identified.(A) The three-dimensional model before mut...
Mitogen-activated protein kinases 1 and 3 (MAPK1 and MAPK3), also called extracellular regulated kin...
For each subject, genotypes of all analyzed variants are shown on a row of three heatmaps that are b...
<p>Protein chains under parallel evolution are denoted in light blue, their functional domains are d...
DOI
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