<p>Shown per infected host, across time, experiment compared to model predictions for integrated model system, and the T7 ODEs alone, on M9 minimal media with glucose, succinate, or acetate as carbon source (growth rates for T7 ODEs alone are , respectively). Error bars are standard deviation of n = 3. For glucose and succinate media the T7 ODEs time course is not visible because it falls directly beneath the integrated simulation line. The lower right panel quantifies the goodness of fit of the integrated simulation and the T7 ODEs alone to experimental observations using normalized mean squared error.</p
<p>(A) Metabolic map and normalized flux dynamics for tryptone, glucose M9, succinate M9, and acetat...
<p>Graph showing the number of unbound phage particles to MAP cells that are infectable (aerobic) an...
<p>Panel A Graph showing the results of the phage assay (PFU ml<sup>−1</sup>; green and purple) and ...
<p>Modeling results overlaid with experimental phage production measurements. The machinery-feasible...
<p>Three independent experiments were carried out. Error-bars indicate standard deviation.</p
<div><p>Viral replication relies on host metabolic machinery and precursors to produce large numbers...
<p>Error bars indicate the standard deviation for three trials. The first phage count (time zero) oc...
<p>PFU per mL are shown at different time points. Values represent the mean of three independent exp...
<p>Initial cell density was set at cells/mL. In the basic model, cell density was constant and was...
<p>All values are means ± standard deviation of three independent experiments.</p
<p>Both phages had an initial concentration of 7 log PFU mL<sup>−1</sup>. Values represent the mean ...
<p>A) Adsorption curve of Acibel004; B) Adsorption curve of Acibel007; C) Single-step growth curve o...
<p>The plot shows data from one of the three cultures in the binding assay, with observed concentrat...
<p> Legend: • experimental data; ___ model simulation; - . - model simulation of susceptible uninfec...
Abstract: Viruses have evolved to efficiently direct the resources of their hosts toward their own r...
<p>(A) Metabolic map and normalized flux dynamics for tryptone, glucose M9, succinate M9, and acetat...
<p>Graph showing the number of unbound phage particles to MAP cells that are infectable (aerobic) an...
<p>Panel A Graph showing the results of the phage assay (PFU ml<sup>−1</sup>; green and purple) and ...
<p>Modeling results overlaid with experimental phage production measurements. The machinery-feasible...
<p>Three independent experiments were carried out. Error-bars indicate standard deviation.</p
<div><p>Viral replication relies on host metabolic machinery and precursors to produce large numbers...
<p>Error bars indicate the standard deviation for three trials. The first phage count (time zero) oc...
<p>PFU per mL are shown at different time points. Values represent the mean of three independent exp...
<p>Initial cell density was set at cells/mL. In the basic model, cell density was constant and was...
<p>All values are means ± standard deviation of three independent experiments.</p
<p>Both phages had an initial concentration of 7 log PFU mL<sup>−1</sup>. Values represent the mean ...
<p>A) Adsorption curve of Acibel004; B) Adsorption curve of Acibel007; C) Single-step growth curve o...
<p>The plot shows data from one of the three cultures in the binding assay, with observed concentrat...
<p> Legend: • experimental data; ___ model simulation; - . - model simulation of susceptible uninfec...
Abstract: Viruses have evolved to efficiently direct the resources of their hosts toward their own r...
<p>(A) Metabolic map and normalized flux dynamics for tryptone, glucose M9, succinate M9, and acetat...
<p>Graph showing the number of unbound phage particles to MAP cells that are infectable (aerobic) an...
<p>Panel A Graph showing the results of the phage assay (PFU ml<sup>−1</sup>; green and purple) and ...