<p>Structures and additional data associated with these hits are presented within <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0047974#pone-0047974-g007" target="_blank">Figure 7</a>.</p
<p>The panels represent an attempt to simulate experimental data from <a href="http://www.plosone.or...
<p>The solid circles are experimental data and the line is the theoretical expression , where are e...
<p>Dose response curve of MMV687146 (A), MMV688508 (B), MMV688844 (C), and MMV688845 (D) and referen...
Abstract: Many screening hits inhibit enzymes with steep dose-response curves, which are considered ...
<p>Of fifteen compounds surviving dose-response potency testing, five commercially-available molecul...
<p><i>Panel A and B:</i> Dose response curves of the selected compound in MPC, MTT and PC12 PHEO cel...
<p>All hit compounds identified were chemical clustered using pubchem finger prints. (A) The major c...
<p>Preliminary hit clustering was based on the EC50 value from the concentration-response curves of ...
<p><b>A–E</b>, concentration-response curves generated from the data obtained in the screen (top pan...
<p>Scatter plot of screening data for a small library of known bioactive small molecules using the P...
For each compound (dots), the relative GFP fluorescence of the screening target in the primary scree...
<p>Experimental data was taken from references [<a href="http://www.ploscompbiol.org/article/info:do...
<p>(<b>A</b>) Heat map showing relative percent infection inhibition (left panel) and percent cell n...
<p>X-axis contains the 4 clusters. Y-axis contains the peak intensity, scaled from 0 (minimum detect...
<p>All agents were tested in at least four independent experiments, run on up to three micro-titer p...
<p>The panels represent an attempt to simulate experimental data from <a href="http://www.plosone.or...
<p>The solid circles are experimental data and the line is the theoretical expression , where are e...
<p>Dose response curve of MMV687146 (A), MMV688508 (B), MMV688844 (C), and MMV688845 (D) and referen...
Abstract: Many screening hits inhibit enzymes with steep dose-response curves, which are considered ...
<p>Of fifteen compounds surviving dose-response potency testing, five commercially-available molecul...
<p><i>Panel A and B:</i> Dose response curves of the selected compound in MPC, MTT and PC12 PHEO cel...
<p>All hit compounds identified were chemical clustered using pubchem finger prints. (A) The major c...
<p>Preliminary hit clustering was based on the EC50 value from the concentration-response curves of ...
<p><b>A–E</b>, concentration-response curves generated from the data obtained in the screen (top pan...
<p>Scatter plot of screening data for a small library of known bioactive small molecules using the P...
For each compound (dots), the relative GFP fluorescence of the screening target in the primary scree...
<p>Experimental data was taken from references [<a href="http://www.ploscompbiol.org/article/info:do...
<p>(<b>A</b>) Heat map showing relative percent infection inhibition (left panel) and percent cell n...
<p>X-axis contains the 4 clusters. Y-axis contains the peak intensity, scaled from 0 (minimum detect...
<p>All agents were tested in at least four independent experiments, run on up to three micro-titer p...
<p>The panels represent an attempt to simulate experimental data from <a href="http://www.plosone.or...
<p>The solid circles are experimental data and the line is the theoretical expression , where are e...
<p>Dose response curve of MMV687146 (A), MMV688508 (B), MMV688844 (C), and MMV688845 (D) and referen...