Screening hits showing significant activity in the MMS cytotoxicity enhancement experiments.

<p>qHTS, IC₅₀ (µM) obtained in the initial quantitative high-throughput screen; Gel, percent incision observed in the presence of 100 µM compound using the radiotracer detection or estimated IC₅₀ value (µM) using the fluorescence detection; FP, IC₅₀ (µM) or annotation of response (N.A., no activity observed; P.C., partial concentration response curve) obtained in the fluorescence polarization displacement assay; MMS, potentiation of the genotoxic effect of methylmethane sulfonate (P, positive).