Alignment of the barnacle p38 MAPK sequence with that of other species.

<p><i>Balanus amphitrite</i> p38 (Ba-p38, JQ277477) was aligned with human p38α (Hs-p38, Q16539.3), <i>Drosophila melanogaster</i> p38α (Dm-p38, NP_477163.1), <i>Suberites domuncula</i> p38 (Sd-p38, CAC80141.1), <i>Caenorhabditis elegans</i> p38 (Ce-p38, AAB00664.1), <i>Hydroides elegans</i> p38 (He-p38, ADC54265.1) and <i>Saccharomyces cerevisiae</i> HOG1 (Sc-HOG1, AAA34680.1). The positions of the subdomains I-XI are indicated. The signature sequences are underlined and diagnostic amino acids are indicated by black arrowheads. Kinase interaction motif and substrate binding sites are shown by red and green colored squares, respectively. Conserved dual phosphorylatable residues are indicated with asterisks.