<p>The yearly number of cases and hospitalizations per 100,000 individuals is estimated in 10-year simulations of dengue transmission when there is no vaccination (baseline), roll-out that covers only individuals ages 2 to 14 years, and roll-out that covers individuals ages 2 to 46 years. The vaccine protects 70% of vaccinees against infection. The cumulative uncomplicated dengue fever cases and severe cases requiring hospitalization averted are relative to the baseline scenario. <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0001876#s3" target="_blank">Results</a> are the averages and standard deviations from fifty stochastic simulations per scenario.</p
<p>Simulated pre-existing immunity to the dengue serotypes in Bang Phae by age. We assume constant r...
"accepted 16-Oct-2013"As the development of a dengue vaccine is ongoing, we simulate an hypothetical...
Dengue vaccines will soon provide a new tool for reducing dengue disease, but the effectiveness of w...
<p>Various fractions of the population (0%, 30%, 50%, and 70%) from 2 to 14 years old or from 2 to 4...
<p>Each plot shows the daily number of newly infected and symptomatic people from a single represent...
<p>The larger points represent the median attack rates (y-axis) of ten stochastic simulations run wh...
<p>Plotted are the average age-specific (A) infection incidence, (B) dengue fever incidence, and (C)...
Simulation pairs varied with respect to the proportion of vaccine efficacy due to protection from in...
Background Large Phase III trials across Asia and Latin America have recently demonstrated the effic...
<div><p>Dengue vaccines will soon provide a new tool for reducing dengue disease, but the effectiven...
BackgroundLarge Phase III trials across Asia and Latin America have recently demonstrated the effica...
Background: Dengue is a mosquito-borne infectious disease that constitutes a growing global threat w...
With approximately 3 billion people at risk of acquiring the infection, dengue fever is now consider...
<p><b>Background</b>: A case-cohort study, using a novel assay and data from three dengue vaccine ef...
<p>Model 1: constant force of infection; Model 2: different forces of infection above and below 6 ye...
<p>Simulated pre-existing immunity to the dengue serotypes in Bang Phae by age. We assume constant r...
"accepted 16-Oct-2013"As the development of a dengue vaccine is ongoing, we simulate an hypothetical...
Dengue vaccines will soon provide a new tool for reducing dengue disease, but the effectiveness of w...
<p>Various fractions of the population (0%, 30%, 50%, and 70%) from 2 to 14 years old or from 2 to 4...
<p>Each plot shows the daily number of newly infected and symptomatic people from a single represent...
<p>The larger points represent the median attack rates (y-axis) of ten stochastic simulations run wh...
<p>Plotted are the average age-specific (A) infection incidence, (B) dengue fever incidence, and (C)...
Simulation pairs varied with respect to the proportion of vaccine efficacy due to protection from in...
Background Large Phase III trials across Asia and Latin America have recently demonstrated the effic...
<div><p>Dengue vaccines will soon provide a new tool for reducing dengue disease, but the effectiven...
BackgroundLarge Phase III trials across Asia and Latin America have recently demonstrated the effica...
Background: Dengue is a mosquito-borne infectious disease that constitutes a growing global threat w...
With approximately 3 billion people at risk of acquiring the infection, dengue fever is now consider...
<p><b>Background</b>: A case-cohort study, using a novel assay and data from three dengue vaccine ef...
<p>Model 1: constant force of infection; Model 2: different forces of infection above and below 6 ye...
<p>Simulated pre-existing immunity to the dengue serotypes in Bang Phae by age. We assume constant r...
"accepted 16-Oct-2013"As the development of a dengue vaccine is ongoing, we simulate an hypothetical...
Dengue vaccines will soon provide a new tool for reducing dengue disease, but the effectiveness of w...