Body weight (A) and heart weight gain (B) as well as heart to body weight ratio (C) of AT2 receptor-deficient (KO) and wild-type (WT) mice during development.

<p>Accelerated cardiac and body weight gain in postnatal KO as compared to WT mice resulting in a significantly reduced heart to body weight ratio of neonatal and adolescent KO mice. In contrast, the heart to body weight ratio of adult eight week-old KO mice is significantly increased. * <i>P</i><0.001 vs. WT (n = 43–233/36–210). Data are shown as mean ± SEM.