Validation of the diagnostic value of SSP411 in serum samples using an ELISA.

<p>(A). Distribution of the serum OD value in cholangiocarcinoma (CC) patients, patients with benign disease and healthy individuals. (B). Receiver operating characteristic (ROC) analysis for the optimal cut-off point for discrimination between between different groups (CC vs. benign; CC vs. benign+normal; benign vs. normal). (C). Distribution of the serum OD values in hepatocellular carcinoma (HCC) patients, patients with liver cirrhosis and healthy individuals. (D). ROC analysis of SSP411 for HCC. (E). ROC analysis results between different CC and HCC groups.