<p>(A) Representative images of zebrafish wild type and morphants. Injection of ATG-MO or SP-MO induced a range of phenotypes, which were grouped in mild and severe, including curly tails (black arrowheads), heart edema and heart malformations (grey arrowheads). (B) Percentages of healthy phenotype, mild phenotype abnormalities, severe phenotype abnormalities and lethality among uninjected control (WT) and MOs-injected morphants. <i>zFbxo7</i> knock down results in decreased zFbxo7 protein expression</p
(A-C) Live images of uninjected and elf3 morpholino injected embryos show development of the eye cup...
<p>(A) Phenotypes of zebrafish embryos not injected (WT; wildtype), injected with control AMO (stand...
<p>MOs were injected into one-cell stage transgenic <i>Tg(cd41:EGFP)</i> zebrafish embryos and assay...
<p>(<b>A–B</b>) Representative images of eye phenotypes induced by injection of <i>chd7</i>-MO in ze...
<p><b>(A-D)</b> Lateral view of wild-type embryos injected with zebrafish <i>tbx20</i>-specific cont...
<p>Zebrafish embryos were either not injected (n.i.) or injected with different quantities of Ctrl. ...
<p>Control-MO injected (<b>E</b>) <i>chd7</i>-MO+<i>chd7</i>-mRNA co-injected (<b>F</b>) zebrafish s...
<p>(A) RT-PCR analysis of zebrafish <i>kif20a</i> gene expression during early stages. <i>Gapdh</i> ...
Atoh8 is a bHLH transcription factor expressed in pancreas, skeletal muscle, the nervous system, and...
<p>Following injection with control morpholino (<i>control MO</i>) or fbxw7 transcription blocking m...
<p>Lateral and ventral view of a zebrafish larvae at 3 dpf injected with either control MO mix (A-B)...
<p>(A–B) Control morpholino (A) and <i>otx1a</i>/<i>otx2</i> morpholino (B) injected embryos photogr...
<p>(A) Schematic representation of the zFbxo7 functional domains. The values underneath each domain ...
<p>Embryos injected with zfTPP1 MO1 were stained with acridine orange and visualized (at 28hpf) unde...
<p>Injected zebrafish embryos were assessed for the incidence of pronephric cysts. (A) Cont MO injec...
(A-C) Live images of uninjected and elf3 morpholino injected embryos show development of the eye cup...
<p>(A) Phenotypes of zebrafish embryos not injected (WT; wildtype), injected with control AMO (stand...
<p>MOs were injected into one-cell stage transgenic <i>Tg(cd41:EGFP)</i> zebrafish embryos and assay...
<p>(<b>A–B</b>) Representative images of eye phenotypes induced by injection of <i>chd7</i>-MO in ze...
<p><b>(A-D)</b> Lateral view of wild-type embryos injected with zebrafish <i>tbx20</i>-specific cont...
<p>Zebrafish embryos were either not injected (n.i.) or injected with different quantities of Ctrl. ...
<p>Control-MO injected (<b>E</b>) <i>chd7</i>-MO+<i>chd7</i>-mRNA co-injected (<b>F</b>) zebrafish s...
<p>(A) RT-PCR analysis of zebrafish <i>kif20a</i> gene expression during early stages. <i>Gapdh</i> ...
Atoh8 is a bHLH transcription factor expressed in pancreas, skeletal muscle, the nervous system, and...
<p>Following injection with control morpholino (<i>control MO</i>) or fbxw7 transcription blocking m...
<p>Lateral and ventral view of a zebrafish larvae at 3 dpf injected with either control MO mix (A-B)...
<p>(A–B) Control morpholino (A) and <i>otx1a</i>/<i>otx2</i> morpholino (B) injected embryos photogr...
<p>(A) Schematic representation of the zFbxo7 functional domains. The values underneath each domain ...
<p>Embryos injected with zfTPP1 MO1 were stained with acridine orange and visualized (at 28hpf) unde...
<p>Injected zebrafish embryos were assessed for the incidence of pronephric cysts. (A) Cont MO injec...
(A-C) Live images of uninjected and elf3 morpholino injected embryos show development of the eye cup...
<p>(A) Phenotypes of zebrafish embryos not injected (WT; wildtype), injected with control AMO (stand...
<p>MOs were injected into one-cell stage transgenic <i>Tg(cd41:EGFP)</i> zebrafish embryos and assay...