<p>Haplotypes are composed of variants rs1502593 (C>T), rs522951 (G>C), rs11190480 (A>G), rs3071 (T>G), rs3793767 (T>C), rs10883463 (T>C), rs508384 (C>A) in that order. A indicates common allele, B indicates rare allele.</p>a<p>based on the 615 participants fasting at blood draw.</p>b<p>geometric means and (95% CI);</p>c<p>means and standard error;</p>d<p>inverse and (95% CI);</p>e<p>based on 2077 participants due to missing biomarker data. All the reported significance levels are nominal P values and are not adjusted for multiple comparisons.</p><p><b>P<sub>add</sub></b>: P for trend or P for the additive model; <b>P<sub>dom</sub></b>: P value for the dominant model. <b>P<sub>rec</sub></b>: P value for the recessive model.</p
Type 2 diabetes (T2D) affects the health of millions of people worldwide. The identification of gene...
<p>The table presents a case-control study of the association of the rs738409 with the metabolic syn...
<p>After removal of <i>ESR1</i> rs9479122, single-SNP tests of association were performed for 2,530,...
<p>Each SNP is coded as 0, 1 and 2 according to the number of minor alleles a participant carries.</...
) could potentially modify metabolic risk factors, but few human studies have addressed this questio...
a<p>Risk alleles for type 2 diabetes in the Caucasian descent population are denoted in bold. OR and...
<p>All phenotypes were standardized prior to analyses. Two regression models were used: Model A incl...
Aims/hypothesis: The heritability of fasting glucose levels in Northern European populations has bee...
<p>The results of linear regression analysis with adjustment for age, sex and BMI are presented.</p>...
<p>rs138726309 (p.His177Tyr), rs2232323 (p.Tyr207Ser), and rs492594 (p.Val219Leu), obtained from 4,4...
<p>Freq = haplotype frequency, Beta = regression coefficient, Stat = Test statistic (T), p = p-value...
a<p>The sequence of the SNPs in the Haplotypes was rs2227983, rs2072454, rs17337023, rs1050171, rs11...
<p>Mean and 95% confidence interval for fasting glucose (<b>Fig. 1a</b>) and glycated hemoglobin (<b...
<p><b>Subcohort</b>: Mean ± SD, %, or median (25<sup>th</sup> percentile; 75<sup>th</sup> percentile...
Association signals in GWAS are usually prioritized solely by p values. Here, we attempt to improve ...
Type 2 diabetes (T2D) affects the health of millions of people worldwide. The identification of gene...
<p>The table presents a case-control study of the association of the rs738409 with the metabolic syn...
<p>After removal of <i>ESR1</i> rs9479122, single-SNP tests of association were performed for 2,530,...
<p>Each SNP is coded as 0, 1 and 2 according to the number of minor alleles a participant carries.</...
) could potentially modify metabolic risk factors, but few human studies have addressed this questio...
a<p>Risk alleles for type 2 diabetes in the Caucasian descent population are denoted in bold. OR and...
<p>All phenotypes were standardized prior to analyses. Two regression models were used: Model A incl...
Aims/hypothesis: The heritability of fasting glucose levels in Northern European populations has bee...
<p>The results of linear regression analysis with adjustment for age, sex and BMI are presented.</p>...
<p>rs138726309 (p.His177Tyr), rs2232323 (p.Tyr207Ser), and rs492594 (p.Val219Leu), obtained from 4,4...
<p>Freq = haplotype frequency, Beta = regression coefficient, Stat = Test statistic (T), p = p-value...
a<p>The sequence of the SNPs in the Haplotypes was rs2227983, rs2072454, rs17337023, rs1050171, rs11...
<p>Mean and 95% confidence interval for fasting glucose (<b>Fig. 1a</b>) and glycated hemoglobin (<b...
<p><b>Subcohort</b>: Mean ± SD, %, or median (25<sup>th</sup> percentile; 75<sup>th</sup> percentile...
Association signals in GWAS are usually prioritized solely by p values. Here, we attempt to improve ...
Type 2 diabetes (T2D) affects the health of millions of people worldwide. The identification of gene...
<p>The table presents a case-control study of the association of the rs738409 with the metabolic syn...
<p>After removal of <i>ESR1</i> rs9479122, single-SNP tests of association were performed for 2,530,...