An increased occurrence of glycine residues occurs where the linkers connect to globular domains.

<p>The probability of finding a glycine residue was determined for the linker sequences in (A) the Eukaryotic GH Family 7, (B) the Eukaryotic GH Family 6, and the Bacterial GH Family 6 datasets (C) with the CBM located at the N-terminus and (D) with the CBM located at the C-terminus. Each sequence was split into 11 sections, or bins, with an approximately equal number of residues in each bin. The number of glycine residues was divided by the total number of sequence positions in each bin.