<p>Relative transcript level responses using human blood from 5 healthy human donors measured by quantitative RT-PCR analysis 24 hrs after 2 Gy exposure with respect to sham (0 Gy) transcript levels. Expression of the sham (0 Gy) and 2 Gy transcript responses were calculated relative to the average expression of <i>ACTB (β-Actin</i>). The delta Ct for <i>β-Actin</i> between sham and 2 Gy irradiated samples was <0.3 for all but one sample, which was excluded from this analysis. The fold-change for each gene between sham and irradiated samples was calculated using the delta-delta Ct method. Similar results were obtained when normalized using <i>GAPDH</i> expression as endogenous control (data not shown).</p
Risk estimation of ionizing radiation in the middle to high dose range has been mainly based on the ...
Molecular biodosimetry tools are a valuable asset for life-saving medical triage and patient managem...
BackgroundIn cancer radiotherapy, knowledge of normal tissue responses and toxicity risks is essenti...
DNA damage and repair are hallmarks of cellular responses to ionizing radiation. We hypothesized tha...
<div><p>DNA damage and repair are hallmarks of cellular responses to ionizing radiation. We hypothes...
<p>Relative gene expression is shown for samples that were either sham irradiated or irradiated with...
Mammalian cells are known to express genes that are associated with repairing damaged DNA. The trans...
<div><p>DNA repair is an essential cellular process required to maintain genomic stability. Every ce...
h Understanding the mechanisms producing low dose ionizing radiation specific bio-logical effects re...
<p>Relative gene expression is shown for samples that were either sham irradiated or irradiated with...
DNA repair is an essential cellular process required to maintain genomic stability. Every cell is su...
DNA repair is an essential cellular process required to maintain genomic stability. Every cell is su...
Humans are exposed to the DNA damaging agent, ionizing radiation (IR), from background radiation, me...
Cells contain many genes that encode proteins which dictate the cell function. The thousands of gene...
Humans are exposed to the DNA damaging agent, ionizing radiation (IR), from background radiation, me...
Risk estimation of ionizing radiation in the middle to high dose range has been mainly based on the ...
Molecular biodosimetry tools are a valuable asset for life-saving medical triage and patient managem...
BackgroundIn cancer radiotherapy, knowledge of normal tissue responses and toxicity risks is essenti...
DNA damage and repair are hallmarks of cellular responses to ionizing radiation. We hypothesized tha...
<div><p>DNA damage and repair are hallmarks of cellular responses to ionizing radiation. We hypothes...
<p>Relative gene expression is shown for samples that were either sham irradiated or irradiated with...
Mammalian cells are known to express genes that are associated with repairing damaged DNA. The trans...
<div><p>DNA repair is an essential cellular process required to maintain genomic stability. Every ce...
h Understanding the mechanisms producing low dose ionizing radiation specific bio-logical effects re...
<p>Relative gene expression is shown for samples that were either sham irradiated or irradiated with...
DNA repair is an essential cellular process required to maintain genomic stability. Every cell is su...
DNA repair is an essential cellular process required to maintain genomic stability. Every cell is su...
Humans are exposed to the DNA damaging agent, ionizing radiation (IR), from background radiation, me...
Cells contain many genes that encode proteins which dictate the cell function. The thousands of gene...
Humans are exposed to the DNA damaging agent, ionizing radiation (IR), from background radiation, me...
Risk estimation of ionizing radiation in the middle to high dose range has been mainly based on the ...
Molecular biodosimetry tools are a valuable asset for life-saving medical triage and patient managem...
BackgroundIn cancer radiotherapy, knowledge of normal tissue responses and toxicity risks is essenti...