ESR spectra of murine- and human- melanoma and healthy tissues.

<p><b>A)</b> Murine B16F10 melanoma cells were injected in 5 mice in order to produce primary melanomas. Mice were sacrificed 14 days after the cell injection and tumours were collected for ESR analysis. The spectra show the presence of a strong signal located at the same position as observed in human melanoma cells. Signal was stable over time (recorded after 2 hours and after 14 days upon frozen storage). <b>B)</b> Murine tissues from liver, kidney and heart do not show ESR signal in the same magnetic field range. <b>C)</b> ESR spectra of formalin-fixed paraffin-embedded sections of human melanoma, human nevus tissue and fresh mouse melanoma tissue. DPPH arrow indicates the position of the standard free radical signal (1, 1-diphenyl-2-picrylhydrazyl).