<p>Transcript level responses measured by quantitative RT-PCR analysis 24 hrs after exposure to 2 Gy, LPS treatment, and combined LPS and 2 Gy of whole blood of <i>CDKN1A</i> (A), <i>BBC3</i> (B), and <i>FDXR</i> (C) genes with respect to transcript levels in un-treated blood cultures. A. A radiation exposure of 2 Gy in the absence of LPS (left panel) or LPS treatment alone (middle panel) induced <i>CDKN1A</i> to approximately the same level at 24 hrs: 7.3 vs 8.2-fold, respectively (T-Test p = 0.47). LPS treatment in the presence of a 2 Gy radiation exposure induced <i>CDKN1A</i> expression ∼10.2-fold (right panel), which is a 1.4-fold increase compared to 2 Gy alone (T-test p = 0.03). B. In the absence of LPS, radiation induced <i>BBC3</i>...
Purpose: Ionizing radiation (IR)-induced transcriptional changes are considered a potential biodosim...
This study was designed to discover blood biomarkers of cancer susceptibility using invasive multipl...
<p>Relative transcript level responses using human blood from 5 healthy human donors measured by qua...
<p>Transcript level responses measured by quantitative RT-PCR analysis 24 hrs after LPS treatment of...
<p>Transcript level responses measured by quantitative RT-PCR analysis 24 hrs after exposure to 2 Gy...
<p>In comparison to untreated sham samples, inflammation in the absence of radiation exposure upregu...
Previous investigations in gene expression changes in blood after radiation exposure have highlighte...
<div><p>DNA damage and repair are hallmarks of cellular responses to ionizing radiation. We hypothes...
Mammalian cells are known to express genes that are associated with repairing damaged DNA. The trans...
Introduction: Formerly, we studied transcriptional alterations in primary human fibroblast cells aft...
This study was designed to discover blood biomarkers of cancer susceptibility using invasive multipl...
This study was designed to discover blood biomarkers of cancer susceptibility using invasive multipl...
Cells contain many genes that encode proteins which dictate the cell function. The thousands of gene...
International audienceFor triage purposes following a nuclear accident, blood-based gene expression ...
<p>(<b>A)</b> LGMN mRNA in SK-BR-3 cells was detected by RT-PCR after 24 hs of radiation exposure. G...
Purpose: Ionizing radiation (IR)-induced transcriptional changes are considered a potential biodosim...
This study was designed to discover blood biomarkers of cancer susceptibility using invasive multipl...
<p>Relative transcript level responses using human blood from 5 healthy human donors measured by qua...
<p>Transcript level responses measured by quantitative RT-PCR analysis 24 hrs after LPS treatment of...
<p>Transcript level responses measured by quantitative RT-PCR analysis 24 hrs after exposure to 2 Gy...
<p>In comparison to untreated sham samples, inflammation in the absence of radiation exposure upregu...
Previous investigations in gene expression changes in blood after radiation exposure have highlighte...
<div><p>DNA damage and repair are hallmarks of cellular responses to ionizing radiation. We hypothes...
Mammalian cells are known to express genes that are associated with repairing damaged DNA. The trans...
Introduction: Formerly, we studied transcriptional alterations in primary human fibroblast cells aft...
This study was designed to discover blood biomarkers of cancer susceptibility using invasive multipl...
This study was designed to discover blood biomarkers of cancer susceptibility using invasive multipl...
Cells contain many genes that encode proteins which dictate the cell function. The thousands of gene...
International audienceFor triage purposes following a nuclear accident, blood-based gene expression ...
<p>(<b>A)</b> LGMN mRNA in SK-BR-3 cells was detected by RT-PCR after 24 hs of radiation exposure. G...
Purpose: Ionizing radiation (IR)-induced transcriptional changes are considered a potential biodosim...
This study was designed to discover blood biomarkers of cancer susceptibility using invasive multipl...
<p>Relative transcript level responses using human blood from 5 healthy human donors measured by qua...