Sulfatide-containing liposomal doxorubicin treatment had significantly reduced myelosuppression.

<p>HT-29 xenograft-bearing mice were treated as indicated in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049277#pone-0049277-g003" target="_blank">Figure 3</a>. Blood was collected immediately after the mice were sacrificed upon reaching the end point. Data shown are means ± S.E. (n = 3∼5). *, <i>P</i>&lt;0.05 compared to saline; ***, <i>P</i>&lt;0.001 compared to saline; #, <i>P</i>&lt;0.05 compared to free DOX; ##, <i>P</i>&lt;0.01 compared to free DOX.