The effect of resveratrol on the proteins involved in MCF-7 and H1299 cell apoptosis.

<p>(A) Activation of caspase 9, caspase 7, and PARP by resveratrol in MCF-7 cells. (B) Levels of caspase 9 and caspase 7 in H1299 cells exposed to resveratrol. For western blotting analysis, the cells were exposed to various concentrations of resveratrol. The data represent 3–4 independent experiments, and the band intensities are graphically represented with each group of images. (C) MCF-7 and H1299 cells were pre-incubated with 50 µM of the caspase inhibitor Z-VAD-FMK for 1 h prior to treatment with various concentrations of <i>trans</i>-resveratrol. The cell viability was measured by the MTT assay. The results (n = 3) are expressed as % of control, and the data shown are mean ± S.E.M. *<i>p</i><0.05 in comparison with the respective control (Student's <i>t</i>-test).