<p>LPS-primed (1 µg/ml, 2 h) bone marrow-derived macrophages from Balb/cJ or NOD/LtJ mice were treated with LT (1 µg/ml) for 60 or 80 min, or with nigericin at indicated doses for 20 min. Cell lysates were analyzed by Western blotting for IL-1β, and the same samples were probed with caspase-1 p10 antibody to detect caspase-1 cleavage.</p
Bone-marrow-derived macrophages (BMDMs) from (A-C) WT mice; (D-F) WT and Caspase-11-/- mice; (G-I) W...
<p>(<b>A</b>) and (<b>C</b>) Procaspase-1 p45 and caspase-1 subunit p20 were detected in cell lysate...
Macrophages highly populate tumour microenvironment and are referred to as tumor-associated macropha...
IL-1β release from WT and NLRP3-deficient BMDM (A) or PMs (B) primed with LPS (200 ng/ml, 3 h), then...
BMMs were isolated from WT, Gsdmd−/−, Nlrp3−/−, Casp1−/−, Casp11−/−, NOMID, or NOMID;Gsdmd−/− mice a...
<p>Macrophages from wild-type (WT) (A, D, G, H), NLRP3-deficient (B, E), and ASC-deficient (C, F) mi...
<p>(<b>A</b>) Gene expression was determined in splenocytes of 3 C57BL/6 or MyD88<sup>−/−</sup> mice...
Cells were incubated under cell culture conditions with the indicated concentrations of ions in the ...
(A) Day 7 bone marrow macrophages prepared from Dicerfl/fl x ERT-Cre- (WT) or Dicerfl/fl x ERT-Cre+ ...
<p>(A) Bone marrow-derived macrophages were cultured from the femurs of C57BL/6 mice, which were eit...
<p>(<b>A</b>-<b>C</b>). J774 macrophages were primed with LPS (100 ng/ml) for 2h. Then, indicated st...
<p>(<b>A</b>) At 9 days post-infection, splenocytes from C57BL/6, and P2X7R<sup>−/−</sup> mice were ...
The caspase-1 protease is a core component of multiprotein inflammasome complexes, which play a crit...
<p><i>A</i>, rpMΦs from <i>Mefv</i><sup>+/+</sup> and <i>Mefv</i><sup>−/−</sup> littermate mice were...
<p><b>A)</b> LDH release assay of MH-S macrophages infected with a high and low MOI of <i>S</i>. <i>...
Bone-marrow-derived macrophages (BMDMs) from (A-C) WT mice; (D-F) WT and Caspase-11-/- mice; (G-I) W...
<p>(<b>A</b>) and (<b>C</b>) Procaspase-1 p45 and caspase-1 subunit p20 were detected in cell lysate...
Macrophages highly populate tumour microenvironment and are referred to as tumor-associated macropha...
IL-1β release from WT and NLRP3-deficient BMDM (A) or PMs (B) primed with LPS (200 ng/ml, 3 h), then...
BMMs were isolated from WT, Gsdmd−/−, Nlrp3−/−, Casp1−/−, Casp11−/−, NOMID, or NOMID;Gsdmd−/− mice a...
<p>Macrophages from wild-type (WT) (A, D, G, H), NLRP3-deficient (B, E), and ASC-deficient (C, F) mi...
<p>(<b>A</b>) Gene expression was determined in splenocytes of 3 C57BL/6 or MyD88<sup>−/−</sup> mice...
Cells were incubated under cell culture conditions with the indicated concentrations of ions in the ...
(A) Day 7 bone marrow macrophages prepared from Dicerfl/fl x ERT-Cre- (WT) or Dicerfl/fl x ERT-Cre+ ...
<p>(A) Bone marrow-derived macrophages were cultured from the femurs of C57BL/6 mice, which were eit...
<p>(<b>A</b>-<b>C</b>). J774 macrophages were primed with LPS (100 ng/ml) for 2h. Then, indicated st...
<p>(<b>A</b>) At 9 days post-infection, splenocytes from C57BL/6, and P2X7R<sup>−/−</sup> mice were ...
The caspase-1 protease is a core component of multiprotein inflammasome complexes, which play a crit...
<p><i>A</i>, rpMΦs from <i>Mefv</i><sup>+/+</sup> and <i>Mefv</i><sup>−/−</sup> littermate mice were...
<p><b>A)</b> LDH release assay of MH-S macrophages infected with a high and low MOI of <i>S</i>. <i>...
Bone-marrow-derived macrophages (BMDMs) from (A-C) WT mice; (D-F) WT and Caspase-11-/- mice; (G-I) W...
<p>(<b>A</b>) and (<b>C</b>) Procaspase-1 p45 and caspase-1 subunit p20 were detected in cell lysate...
Macrophages highly populate tumour microenvironment and are referred to as tumor-associated macropha...