<p>A scatter plot with a line of best fit demonstrates that each gene in the PFC shows either increase or decrease in expression across age (qv <0.05). X-axis: Age (log 2 scale). Y-axis: Gene expression (log 2 scale). Subjects were color-coded as red: neonate (0–3 months), green: infant (3–12 months), blue: toddler (1–5 years), light blue: school age (6–13 years), pink: teenage (14–19 years), yellow: young adult (20–30 years), and grey: adult (31–50 years). A: <i>MAOB</i> (monoamine oxidase B), B: <i>NDUFV1</i> [NADH dehydrogenase (ubiquinone) flavoprotein 1, 51 kDa], C: <i>SLC25A14</i> (mitochondrial uncoupling protein 5), D: <i>TUBB3</i> (tubulin beta-3 chain).</p
(A) and (B) Mean mtDNA ratio relative to nucDNA (mt/nuc DNA) in heart, and liver of the SUS and RES ...
AIM: To provide a detailed gene and protein expression analysis related to mitochondrial biogenesis ...
<p>2A: Quantitative PCR analysis: PRC (PPRC1) and PGC-1α (PPARGC1A) coactivators, NRF-1 transcriptio...
<p>For each gene: fold values (FC) and p value obtained in p43−/− mice versus respective controls. S...
<p>(a) Western blot of mitochondrial OXPHOS proteins from wildtype and transgenic littermates, befor...
To identify potential markers of aging, we compared the expression of a set of genes involved in mit...
Ageing is a predictable, universal and detrimental process in humans. The ‘mitochondrial theory of a...
<p>Relative log2 fold changes of mRNA were presented comparing late middle-aged (18months old) to yo...
<p>(A, B) The leukocytic mtDNA content was associated with the <i>AluYb8MUTYH</i> variant. The relat...
AbstractWe studied the effect of ageing on the mRNA levels of mitochondria-encoded polypeptides in h...
<p>(<b>A</b>) The mtDNA mutation frequency is greater in young thoraces than in young heads (**p<0.0...
Background: The quantitative loss of mitochondrial DNA (mtDNA) known as mtDNA depletion, often gives...
<p>The volcano plot is an arbitrary representation (proposed by the web-based RT<sup>2</sup> prolife...
Background and aims: Individuals of the same species may have large variations in their ageing rates...
A. Overrepresented nucleotides in tri- (left) or pentanucleotide (right) motifs flanking CG to TA tr...
(A) and (B) Mean mtDNA ratio relative to nucDNA (mt/nuc DNA) in heart, and liver of the SUS and RES ...
AIM: To provide a detailed gene and protein expression analysis related to mitochondrial biogenesis ...
<p>2A: Quantitative PCR analysis: PRC (PPRC1) and PGC-1α (PPARGC1A) coactivators, NRF-1 transcriptio...
<p>For each gene: fold values (FC) and p value obtained in p43−/− mice versus respective controls. S...
<p>(a) Western blot of mitochondrial OXPHOS proteins from wildtype and transgenic littermates, befor...
To identify potential markers of aging, we compared the expression of a set of genes involved in mit...
Ageing is a predictable, universal and detrimental process in humans. The ‘mitochondrial theory of a...
<p>Relative log2 fold changes of mRNA were presented comparing late middle-aged (18months old) to yo...
<p>(A, B) The leukocytic mtDNA content was associated with the <i>AluYb8MUTYH</i> variant. The relat...
AbstractWe studied the effect of ageing on the mRNA levels of mitochondria-encoded polypeptides in h...
<p>(<b>A</b>) The mtDNA mutation frequency is greater in young thoraces than in young heads (**p<0.0...
Background: The quantitative loss of mitochondrial DNA (mtDNA) known as mtDNA depletion, often gives...
<p>The volcano plot is an arbitrary representation (proposed by the web-based RT<sup>2</sup> prolife...
Background and aims: Individuals of the same species may have large variations in their ageing rates...
A. Overrepresented nucleotides in tri- (left) or pentanucleotide (right) motifs flanking CG to TA tr...
(A) and (B) Mean mtDNA ratio relative to nucDNA (mt/nuc DNA) in heart, and liver of the SUS and RES ...
AIM: To provide a detailed gene and protein expression analysis related to mitochondrial biogenesis ...
<p>2A: Quantitative PCR analysis: PRC (PPRC1) and PGC-1α (PPARGC1A) coactivators, NRF-1 transcriptio...