<p>(A) Mouse lumbar spinal cord sections were stained with anti-FUS/TLS antibody, and followed by the incubation with Alexa568 conjugated secondary antibody (Invitrogen). Sections were then stained with DAPI. Images were obtained using fluorescence microscopy. Square indicates the anterior horn of spinal cord section. Bars, 200 µm. (B) Mouse lumbar spinal cord sections were co-stained with indicated antibodies, followed by the incubation with Alexa568 and Alexa488 conjugated secondary antibody (Invitrogen). Sections were then stained with DAPI. Images were obtained using fluorescence microscopy. Bars, 20 µm.</p
<p>HE staining (A, D, G, J, M, P) shows inflammatory infiltration (arrow heads), and KB staining (B,...
<p>Sections of lumbar spinal cord from CGRPα-GFP<sup>+/−</sup> mice were stained with antibodies to ...
International audienceIn inherited neurodegenerative disorders the engineering of genetically modifi...
<p>(A) Co-immunoprecipitation assay between HA-tagged FUS/TLS and Myc-tagged PRMT1 protein. HEK293 c...
Supplemental Experimental Procedures raised against the C terminus of human TLS (TLS-C), mouse mono-...
<p>Immunohistochemical staining of the spinal cord with anti-Ptprz-S (left panels) and anti-RPTPβ (r...
<p>Images A1, B1, C1 were taken from an animal after injections of PRV-614. A<b>1</b> showed neurons...
Tamoxifen was intraperitoneally injected into the pregnant Brn3bCreERT/+;Ai9 mice from E10.5 to E14....
<p>(A) Representative sagittal sections of lumbar spinal cords from vehicle-treated or 1V136-treated...
<p>Sections of lumbar L4 and L5 DRGs were double-stained with markers for the different subpopulatio...
<p>Immunofluorescence for C4F6 (A, D, green), 14-3-3β (B, red), and 14-3-3γ (E, red), double immunof...
<p>The FLAG-tagged SOD1 and the ligand proteins were immunoprecipitated using the FLAG affinity resi...
<p>(A) Immunofluorescent labeling of spinal cord primary astrocytes from non transgenic (-), transge...
<p>Sections of lumbar spinal cord from CGRPα-GFP<sup>+/−</sup> mice were stained with (A–F) antibodi...
<p>Lumbar mouse spinal cord 8 µm paraffin sections stained with thionin. [A] Transverse section. [B]...
<p>HE staining (A, D, G, J, M, P) shows inflammatory infiltration (arrow heads), and KB staining (B,...
<p>Sections of lumbar spinal cord from CGRPα-GFP<sup>+/−</sup> mice were stained with antibodies to ...
International audienceIn inherited neurodegenerative disorders the engineering of genetically modifi...
<p>(A) Co-immunoprecipitation assay between HA-tagged FUS/TLS and Myc-tagged PRMT1 protein. HEK293 c...
Supplemental Experimental Procedures raised against the C terminus of human TLS (TLS-C), mouse mono-...
<p>Immunohistochemical staining of the spinal cord with anti-Ptprz-S (left panels) and anti-RPTPβ (r...
<p>Images A1, B1, C1 were taken from an animal after injections of PRV-614. A<b>1</b> showed neurons...
Tamoxifen was intraperitoneally injected into the pregnant Brn3bCreERT/+;Ai9 mice from E10.5 to E14....
<p>(A) Representative sagittal sections of lumbar spinal cords from vehicle-treated or 1V136-treated...
<p>Sections of lumbar L4 and L5 DRGs were double-stained with markers for the different subpopulatio...
<p>Immunofluorescence for C4F6 (A, D, green), 14-3-3β (B, red), and 14-3-3γ (E, red), double immunof...
<p>The FLAG-tagged SOD1 and the ligand proteins were immunoprecipitated using the FLAG affinity resi...
<p>(A) Immunofluorescent labeling of spinal cord primary astrocytes from non transgenic (-), transge...
<p>Sections of lumbar spinal cord from CGRPα-GFP<sup>+/−</sup> mice were stained with (A–F) antibodi...
<p>Lumbar mouse spinal cord 8 µm paraffin sections stained with thionin. [A] Transverse section. [B]...
<p>HE staining (A, D, G, J, M, P) shows inflammatory infiltration (arrow heads), and KB staining (B,...
<p>Sections of lumbar spinal cord from CGRPα-GFP<sup>+/−</sup> mice were stained with antibodies to ...
International audienceIn inherited neurodegenerative disorders the engineering of genetically modifi...