Inferred haplotypes in the <i>CCL2</i> locus and their frequency.

<p>Only haplotypes with frequency greater than 2% in any population are shown. Data were downloaded from the Hapmap web site (<a href="http://hapmap.ncbi.nlm.nih.gov/" target="_blank">http://hapmap.ncbi.nlm.nih.gov/</a>) and haplotypes inferred using the ARLEQUIN program. Only the reference polymorphisms that were shared by all the population groups examined were used to generate the haplotypes. Population description is as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049498#pone-0049498-t003" target="_blank">Table 3</a>. The numbers within the parenthesis indicate the number of individuals (n). The h18, h19, h20, h21, h22 were present exclusively in the YRI each with a frequency of 0.0045. h7 and h8 were present exclusively in CEU each with a frequency of 0.0045. h12 and h13 were present exclusively in CHB each with a frequency of 0.0061. h14 was exclusively present in JPT at a frequency of 0.0059. The haplotype frequency of h10 was 0.005 in CEU, 0.006 in CHB, and 0.009 in YRI. The haplotype frequency of h11 was 0.005 in CEU, 0.012 in CHB, and 0.012 in JPT. The ancestral state of the reference SNPs (Anc.) was obtained from the dBSNP database (<a href="http://www.ncbi.nlm.nih.gov/projects/SNP/" target="_blank">http://www.ncbi.nlm.nih.gov/projects/SNP/</a>).