<p>A, immunoprecipitation and western blot showed tyrosine phosphorylation of JNK and ERK were increased in PTPRM knockdown cells, which exhibited no effect on PLCγ phosphorylation. Relative intensity of bands from three western blots was analysed using Image J software for PLCγ (B), JNK (C), and ERK (D). *, <i>p</i><0.05.</p
<p>Cells overexpressing LPA<sub>1</sub> (black, circles), LPA<sub>2</sub> (blue, squares) or LPA<sub...
Regulation of phosphatidylinositol I-kinase (PtdIns 4-kinase) by protein tyrosine phosphorylation ha...
<p>U87MG cells expressing WT-PTEN, C124S-PTEN or G129E-PTEN and mock-treated were incubated in high ...
<p>Representative western blot analyses of total (pan) and phosphorylated (p) ERK (A) and JNK (B and...
<p>A–D) PVTL-1 cells were left untreated as control or treated with 1 µM JakI-1, 5 µM imatinib, or 1...
<p>Immunoblot imaging (A) and statistical analysis (B) for p-ERK 1/2 signaling pathways. The statist...
<p>LCL-WT and DG75 cell lines were treated with PP2 (8 µM), compound 5 (0.05 µM), CI-1040 (4 µM) or ...
<p>EL4 T cells were incubated in DMEM medium with an immobilized anti-CD3/CD28 mAb in the presence o...
<p>(<b>A</b>) Western blot analysis showing phospho-Akt to Akt and phospho-ERK-1/2 to ERK-1/2 ratio ...
<p>Representative Western blot analyses of total cell lysates from HaCaT (left panels) and A431-AD (...
<p>Both experiments were conducted in LNCaP cells. (A) Protein phosphorylation in cells treated with...
<p>(A) Western blot analysis of the phosphorylation of AKT. (B) Western blot analysis of the phospho...
<p>Panel <b>A</b> shows inhibition of light chain (LC)-stimulated phosphorylation of ERK ½, and pane...
<p><b>A–D:</b> THP-1 cells, expressing either non-targeting control shRNA or PTPN22 targeting shRNA,...
<p>(A) Western blotting analysis of p-c-Jun, T-c-Jun and cytochrome c in SH-SY5Y cell extracts after...
<p>Cells overexpressing LPA<sub>1</sub> (black, circles), LPA<sub>2</sub> (blue, squares) or LPA<sub...
Regulation of phosphatidylinositol I-kinase (PtdIns 4-kinase) by protein tyrosine phosphorylation ha...
<p>U87MG cells expressing WT-PTEN, C124S-PTEN or G129E-PTEN and mock-treated were incubated in high ...
<p>Representative western blot analyses of total (pan) and phosphorylated (p) ERK (A) and JNK (B and...
<p>A–D) PVTL-1 cells were left untreated as control or treated with 1 µM JakI-1, 5 µM imatinib, or 1...
<p>Immunoblot imaging (A) and statistical analysis (B) for p-ERK 1/2 signaling pathways. The statist...
<p>LCL-WT and DG75 cell lines were treated with PP2 (8 µM), compound 5 (0.05 µM), CI-1040 (4 µM) or ...
<p>EL4 T cells were incubated in DMEM medium with an immobilized anti-CD3/CD28 mAb in the presence o...
<p>(<b>A</b>) Western blot analysis showing phospho-Akt to Akt and phospho-ERK-1/2 to ERK-1/2 ratio ...
<p>Representative Western blot analyses of total cell lysates from HaCaT (left panels) and A431-AD (...
<p>Both experiments were conducted in LNCaP cells. (A) Protein phosphorylation in cells treated with...
<p>(A) Western blot analysis of the phosphorylation of AKT. (B) Western blot analysis of the phospho...
<p>Panel <b>A</b> shows inhibition of light chain (LC)-stimulated phosphorylation of ERK ½, and pane...
<p><b>A–D:</b> THP-1 cells, expressing either non-targeting control shRNA or PTPN22 targeting shRNA,...
<p>(A) Western blotting analysis of p-c-Jun, T-c-Jun and cytochrome c in SH-SY5Y cell extracts after...
<p>Cells overexpressing LPA<sub>1</sub> (black, circles), LPA<sub>2</sub> (blue, squares) or LPA<sub...
Regulation of phosphatidylinositol I-kinase (PtdIns 4-kinase) by protein tyrosine phosphorylation ha...
<p>U87MG cells expressing WT-PTEN, C124S-PTEN or G129E-PTEN and mock-treated were incubated in high ...