<p>The interactions are translated into pharmacophore features while the binding site amino acids are translated into excluded volumes. The shape of the binding site is also added to increase sensitivity of the pharmacophore.</p
pharmacophore is the “ensemble of steric and electronic features that is necessary to ensure the opt...
<p>The key pharmacophoric features generated from the binding modes of (A) C1 and (B) Ang I. The ami...
Pharmacophore models are an accurate and minimal tridimensional abstraction of intermolecular intera...
A pharmacophore describes the arrangement of molecular features a ligand must contain to efficacious...
Pharmacophore modelling is a well-known structure based drug design method allowing fast virtual scr...
Development towards integrated computer-aided drug design methodologies is presented by utilising cr...
Two approaches are commonly used to model a binding site in rational drug design: On the one hand, s...
Pharmacophoresthree-dimensional (3D) arrangements of essential features enabling a molecule to exert...
Pharmacophoresthree-dimensional (3D) arrangements of essential features enabling a molecule to exert...
Pharmacophoresthree-dimensional (3D) arrangements of essential features enabling a molecule to exert...
Pharmacophoresthree-dimensional (3D) arrangements of essential features enabling a molecule to exert...
<p>The pharmacophore is formed by two hydrogen-bond acceptors (<i>i.e.</i>, <b>A1</b> and <b>A2</b>)...
A pharmacophore is an abstract description of molecular features which are necessary for molecular r...
A detection of the three-dimensional binding mode between a protein and a chemical compound is valua...
<p>Pharmacophoric interaction of most active compound 9s onto the pharmacophore obtained from struct...
pharmacophore is the “ensemble of steric and electronic features that is necessary to ensure the opt...
<p>The key pharmacophoric features generated from the binding modes of (A) C1 and (B) Ang I. The ami...
Pharmacophore models are an accurate and minimal tridimensional abstraction of intermolecular intera...
A pharmacophore describes the arrangement of molecular features a ligand must contain to efficacious...
Pharmacophore modelling is a well-known structure based drug design method allowing fast virtual scr...
Development towards integrated computer-aided drug design methodologies is presented by utilising cr...
Two approaches are commonly used to model a binding site in rational drug design: On the one hand, s...
Pharmacophoresthree-dimensional (3D) arrangements of essential features enabling a molecule to exert...
Pharmacophoresthree-dimensional (3D) arrangements of essential features enabling a molecule to exert...
Pharmacophoresthree-dimensional (3D) arrangements of essential features enabling a molecule to exert...
Pharmacophoresthree-dimensional (3D) arrangements of essential features enabling a molecule to exert...
<p>The pharmacophore is formed by two hydrogen-bond acceptors (<i>i.e.</i>, <b>A1</b> and <b>A2</b>)...
A pharmacophore is an abstract description of molecular features which are necessary for molecular r...
A detection of the three-dimensional binding mode between a protein and a chemical compound is valua...
<p>Pharmacophoric interaction of most active compound 9s onto the pharmacophore obtained from struct...
pharmacophore is the “ensemble of steric and electronic features that is necessary to ensure the opt...
<p>The key pharmacophoric features generated from the binding modes of (A) C1 and (B) Ang I. The ami...
Pharmacophore models are an accurate and minimal tridimensional abstraction of intermolecular intera...
DOI
Add to ORKG