Fc-FGF21(RG) was resistant to aggregation.
- Randy Hecht (117873)
- Yue-Sheng Li (117877)
- Jeonghoon Sun (117881)
- Ed Belouski (117884)
- Michael Hall (117887)
- Todd Hager (117889)
- Junming Yie (117890)
- Wei Wang (17594)
- Dwight Winters (117892)
- Stephen Smith (117894)
- Chris Spahr (117896)
- Lei-Ting Tam (117897)
- Zhongnan Shen (117899)
- Shanaka Stanislaus (117901)
- Narumol Chinookoswong (117903)
- Yvonne Lau (117907)
- Allen Sickmier (117911)
- Mark Leo Michaels (117917)
- Thomas Boone (117922)
- Murielle M. Véniant (117927)
- Jing Xu (15337)
Publication date
November 2012
DOIAbstract
<p>(A) Size exclusion chromatography (SEC) of native FGF21, Fc-FGF21 wild type and Fc-FGF21(RG) concentrated at 65 mg/ml stored at 25°C for various days. (B-C) Aggregation rate of FGF21 (closed circle), Fc-FGF21 (opened circle) or Fc-FGF21(RG) (closed triangular) at 65 mg/ml stored at either 25°C (B) or 4°C (C). (D–E) Aggregation rate of Fc-FGF21 (closed circle), Fc-FGF21(L98R) (opened circle) or Fc-FGF21(RG) (closed triangular) at 65 mg/ml stored at either 25°C (D) or 4°C (E).</p
Add to ORKG