Specific genes and proteins that differ in relative amounts according to disease state.

<p>Relative Abundance of mucin-desulfating sulfatase (Mds), RagB and SusC/D, Outer Membrane Protein A (OmpA), TonB, Short-Chain Fatty Acid production (SCFA) and Butyrate production in (<b>A</b>) metagenomes and (<b>B</b>) MM metaproteomes. Error bars in (A) and (B) represent the standard error of the mean of the samples from Healthy (3 MG, 4 MP), ICD (5 MG, 6 MP) and CCD (2 MG/MP). (<b>C</b>) Specific outer membrane proteins and proteins involved in SCFA pathway that differed between disease categories. Protein abundances were calculated as normalized spectral abundance using the HMRG database search. The presence-absence heatmap indicates which of the 51 bacterial strains each protein matched to in the HMRG database search: black = species present, white = species absent. Grey = Healthy, Blue = CCD, Red = ICD.