Genetic interactions between H2B ubiquitination machinery and canonical splicing factors.

<p>(A) Synthetic growth analyses between <i>bre1Δ</i> and genes encoding splicing factors. Double mutants were generated by tetrad dissection; log-phase cultures of the indicated strains were serially diluted and grown at the indicated temperatures. To the right of panels is the name of the spliceosomal complex to which the splicing factor mutants belong. NTC: Nineteen Complex. (B) Growth analyses of <i>ubp8Δ</i> and genes encoding splicing factors. Double mutants were generated and analyzed as in (A).