<p>The system size is and the mutation rate is . The simulation was carried out for time steps. Each data point is an average over time steps.</p
<p>Mutation accumulation was modeled as a sequential process in which each genotype can acquire a si...
<p>A) Number of remaining diseases (red color) and the expansion of the dominant disease (green co...
<p>Simulations are for , (top) on and for (bottom). In the plots of average perspectives of coope...
<p>The system size is and the mutation rates are and , respectively. Simulation lasts for time st...
<p>a) Changes in the number of cells in each cell population over time, averaged over 50 simulations...
<p>The parameters are , , and . The simulation was carried out for time steps. Each data point is ...
<p>Other parameters are fixed as and . The simulation lasts for time steps. The black squares and ...
<p><b>A</b>) Transitions between the three types considered, wild types (W), resistant types without...
<p>For each combination of <i>U</i> ( = 0.1, 0.3, and 0.5) and <i>s</i> ( = 0.01 and 0.1), simulatio...
<p><b>A</b>) Simulations were initialized with 10<sup>5</sup> cells in all locations. The migration ...
(A) The variance of the transcription levels across 10,000 simulations in which L is linearly decrea...
A and B: The time evolution of different strategies resulted from the replicator-mutator dynamics A ...
Three sets of initial conditions are described in the text. These converge to similar distributions ...
<p>Parameter choices are , , and simulations were performed on a lattice. Trajectories are average...
Trajectories of mean fitness loss for additive and recessive mutation models over time (panels A and...
<p>Mutation accumulation was modeled as a sequential process in which each genotype can acquire a si...
<p>A) Number of remaining diseases (red color) and the expansion of the dominant disease (green co...
<p>Simulations are for , (top) on and for (bottom). In the plots of average perspectives of coope...
<p>The system size is and the mutation rates are and , respectively. Simulation lasts for time st...
<p>a) Changes in the number of cells in each cell population over time, averaged over 50 simulations...
<p>The parameters are , , and . The simulation was carried out for time steps. Each data point is ...
<p>Other parameters are fixed as and . The simulation lasts for time steps. The black squares and ...
<p><b>A</b>) Transitions between the three types considered, wild types (W), resistant types without...
<p>For each combination of <i>U</i> ( = 0.1, 0.3, and 0.5) and <i>s</i> ( = 0.01 and 0.1), simulatio...
<p><b>A</b>) Simulations were initialized with 10<sup>5</sup> cells in all locations. The migration ...
(A) The variance of the transcription levels across 10,000 simulations in which L is linearly decrea...
A and B: The time evolution of different strategies resulted from the replicator-mutator dynamics A ...
Three sets of initial conditions are described in the text. These converge to similar distributions ...
<p>Parameter choices are , , and simulations were performed on a lattice. Trajectories are average...
Trajectories of mean fitness loss for additive and recessive mutation models over time (panels A and...
<p>Mutation accumulation was modeled as a sequential process in which each genotype can acquire a si...
<p>A) Number of remaining diseases (red color) and the expansion of the dominant disease (green co...
<p>Simulations are for , (top) on and for (bottom). In the plots of average perspectives of coope...