<p>Cells were maintained for 48 hours in the presence/absence of isoquercitrin and absorbance at OD<sub>490 nm</sub> was calculated for the cell lysates according to Rho G-Lisa assay. <b>A,</b> Isoquercitrin dose dependent graph; <b>B,</b> Effects of isoquercitrin on RhoA activity alone and in combination with Rho/ROCK inhibitors (n = 3, one-way ANOVA, ** p<0.01; **** p<0.0001). Data are shown as means ± s.e.m.</p
<p>HaCaT cells were treated with SNP (10 μM), a cGMP agonist (8-Br-cGMP, 1 μM) or a PKG agonist (8-p...
<p>(A-C) The levels of GTP-bound Rac1, Cdc42 and RhoA were measured in A549 cells treated with 5 μM ...
<p>(A) Pull-down assay of Rho family proteins showed that knockdown of CTHRC1 inhibited the activati...
<p><b>Upper left,</b> The fluorescent images (acquired with 63× oil objective) show immune-staining ...
<p>Compounds were selected from a pocket directed virtual screen and tested on Glioblastoma cells (1...
<p><i>rhoA</i> gene expression is down-regulated, while expression of <i>rhoQ</i> (TC10) is upregula...
<p><b>A,</b> Quantification of neurite length/cell upon addition of isoquercitrin alone or in combin...
<p>(A) A RhoA bead pull down assay revealed lowered levels of activated RhoA in Ibuprofen treated ce...
<p>A) A RhoGTPase pull-down assay before and after Gleevec treatment (20 µM). NBT-II cells were cult...
<p>(<b>A</b>) Parental 786.0, neo control clones and Activin B knockdown clones were plated in the p...
<p>MDA-MB-231 cells (A, C, E and F) or MDA-MB-468 cells (B and D) were treated with AFOH at the indi...
<p>(A) RhoA activity was assayed in cells treated with E2 (10<sup>−8</sup> M) for 15 min in the pres...
<p><b>A</b> and <b>C:</b> Serum-starved human TM cells were incubated on chamber glass slides coated...
<p>(A) Representative phase-contrast micrographs of U87MG cells left untreated (control) or treated ...
<p><b>A.</b> The localized patterns of E-cadherin and b-catenin were examined using specific antibod...
<p>HaCaT cells were treated with SNP (10 μM), a cGMP agonist (8-Br-cGMP, 1 μM) or a PKG agonist (8-p...
<p>(A-C) The levels of GTP-bound Rac1, Cdc42 and RhoA were measured in A549 cells treated with 5 μM ...
<p>(A) Pull-down assay of Rho family proteins showed that knockdown of CTHRC1 inhibited the activati...
<p><b>Upper left,</b> The fluorescent images (acquired with 63× oil objective) show immune-staining ...
<p>Compounds were selected from a pocket directed virtual screen and tested on Glioblastoma cells (1...
<p><i>rhoA</i> gene expression is down-regulated, while expression of <i>rhoQ</i> (TC10) is upregula...
<p><b>A,</b> Quantification of neurite length/cell upon addition of isoquercitrin alone or in combin...
<p>(A) A RhoA bead pull down assay revealed lowered levels of activated RhoA in Ibuprofen treated ce...
<p>A) A RhoGTPase pull-down assay before and after Gleevec treatment (20 µM). NBT-II cells were cult...
<p>(<b>A</b>) Parental 786.0, neo control clones and Activin B knockdown clones were plated in the p...
<p>MDA-MB-231 cells (A, C, E and F) or MDA-MB-468 cells (B and D) were treated with AFOH at the indi...
<p>(A) RhoA activity was assayed in cells treated with E2 (10<sup>−8</sup> M) for 15 min in the pres...
<p><b>A</b> and <b>C:</b> Serum-starved human TM cells were incubated on chamber glass slides coated...
<p>(A) Representative phase-contrast micrographs of U87MG cells left untreated (control) or treated ...
<p><b>A.</b> The localized patterns of E-cadherin and b-catenin were examined using specific antibod...
<p>HaCaT cells were treated with SNP (10 μM), a cGMP agonist (8-Br-cGMP, 1 μM) or a PKG agonist (8-p...
<p>(A-C) The levels of GTP-bound Rac1, Cdc42 and RhoA were measured in A549 cells treated with 5 μM ...
<p>(A) Pull-down assay of Rho family proteins showed that knockdown of CTHRC1 inhibited the activati...