Responses of striatal and thalamic neurons to stimulation with trains of light stimuli.

<p>Examples of peri-stimulus time histograms and raster diagrams of responses to light stimulation in the putamen (A, B) and VL (C, D). A, B, D: single units; C: multi-unit. Traces are aligned to the start of light stimulation trains (10 pulses, 20 ms each, 30 Hz), indicated by blue lines. Bin size is 8.125 ms. E: Proportion of responses to light stimulation in each structure. ‘Comb.’ denotes an increase followed by a decrease in firing. F: Distribution of responding cells in relation to the closest injection site. In VL, the closest distance examined was 0.5 mm from the injection site (no optrode tracks at 0 mm, indicated by an asterisk). G: Magnitude of light-evoked increases in firing, expressed as the number of spikes during the stimulation train divided by the number of spikes during the baseline period (means + SD, * p<0.001, Mann-Whitney test).