<p>Analyses were performed in tibia growth plates collected on day 13 (48 hrs post-treatment) in C57B and NMRI mice. Btz = bortezomib; Prolif. = Proliferative chondrocytes; Hyp = Hypertrophic chondrocytes. Data represents mean±SEM, n = 5–6 per group.</p>a<p>p≤0.05;</p>b<p>p≤0.01;</p>c<p>p≤0.001 compared to vehicle treated animals of the same strain.</p
<p><b>A.</b> Representative μCT images (top panel) and morphometric analyses (bottom panel) of trabe...
<p>Biomechanical testing of bone strength was performed by 3-point bending analyses in C57B and NMRI...
<p>(A) Femoral growth plate from five-week-old mice, stained with safranin O solution. The growth pl...
<p>Representative pictures of mouse tibia growth plates on day 13 (<b>A</b>) and at termination of t...
<p>pQCT was used to determine the trabecular BMD in the metaphyseal region of the left tibia and cor...
The purpose of this study was to investigate growth plate dynamics in surgical and loading murine mo...
<p><b>A)</b> Representative micrographs of apoptosis in tibia growth plate cartilage on day 13 in ve...
<p>(A) Histological analysis of the metatarsi and tibia (2-week-old, upper panels, and 8-week-old, l...
<p>8 week old NT3.catK mice were labeled calcein 9 and 2 days prior to sacrifice. Left tibias were f...
<p>Values are mean ± SD, n = 8/group. A = Bone mineral density (BMD); B = Mean total cross-section...
<p>Mice were administered tamoxifen at P4-7 and P14-17. (A-B and A’-B’) H&E staining of tibial growt...
<p>(A) Tibial growth plate sections from female mice were stained with Alcian Blue to detect any alt...
<p>Sections of the tibia from 8-week-old mice injected with tamoxifen for 4 weeks were analyzed by h...
<p>Male mice (N = 6–8 per group) were given daily injections of vehicle or 30 or 80 ug/kg PTH(1–34) ...
<p>(A–H) Col 2, Col 10, Cbfa1 and OC immunoreactivity in the tibia epiphyses. Immunolocalization (br...
<p><b>A.</b> Representative μCT images (top panel) and morphometric analyses (bottom panel) of trabe...
<p>Biomechanical testing of bone strength was performed by 3-point bending analyses in C57B and NMRI...
<p>(A) Femoral growth plate from five-week-old mice, stained with safranin O solution. The growth pl...
<p>Representative pictures of mouse tibia growth plates on day 13 (<b>A</b>) and at termination of t...
<p>pQCT was used to determine the trabecular BMD in the metaphyseal region of the left tibia and cor...
The purpose of this study was to investigate growth plate dynamics in surgical and loading murine mo...
<p><b>A)</b> Representative micrographs of apoptosis in tibia growth plate cartilage on day 13 in ve...
<p>(A) Histological analysis of the metatarsi and tibia (2-week-old, upper panels, and 8-week-old, l...
<p>8 week old NT3.catK mice were labeled calcein 9 and 2 days prior to sacrifice. Left tibias were f...
<p>Values are mean ± SD, n = 8/group. A = Bone mineral density (BMD); B = Mean total cross-section...
<p>Mice were administered tamoxifen at P4-7 and P14-17. (A-B and A’-B’) H&E staining of tibial growt...
<p>(A) Tibial growth plate sections from female mice were stained with Alcian Blue to detect any alt...
<p>Sections of the tibia from 8-week-old mice injected with tamoxifen for 4 weeks were analyzed by h...
<p>Male mice (N = 6–8 per group) were given daily injections of vehicle or 30 or 80 ug/kg PTH(1–34) ...
<p>(A–H) Col 2, Col 10, Cbfa1 and OC immunoreactivity in the tibia epiphyses. Immunolocalization (br...
<p><b>A.</b> Representative μCT images (top panel) and morphometric analyses (bottom panel) of trabe...
<p>Biomechanical testing of bone strength was performed by 3-point bending analyses in C57B and NMRI...
<p>(A) Femoral growth plate from five-week-old mice, stained with safranin O solution. The growth pl...