Anti- and pro-apoptotic gene expressions in GEM-R and GEM-S cell lines after combined treatment.

<p>The relative log₂ fold change for anti-apoptotic gene cluster (A–B) and pro-apoptotic gene cluster (C–D), treated with gemcitabine alone (Gem) and in combination with gossypol (Gem+GOS). Only genes that were significantly differentially expressed from control untreated group are represented in the graph. All values on the y-axis were compared to the untreated controls of respective cell lines. Values above zero indicated genes that were up-regulated in its expression. Values below zero indicated genes that were down-regulated in its expression and values at zero indicated no change to gene expression. The log₂ levels of associated genes were normalized to the untreated sample.