UA induced formation of autophagosome vacuoles.

<p>Induction of autophagic vacuoles, with double membranes characteristic of autophagosomes, was detected by electron microscopy in T47D cells after treatment with UA (2.5 and 5.0 µg/mL; DMSO 0.1%) for 24 hours. Black arrows indicate autophagic vacuoles, white arrows indicate double membrane formation.