Evaluation of cytotoxic functions of NK cells in ICU patients.
- Jean-Marie Forel (64985)
- Laurent Chiche (6463)
- Guillemette Thomas (113510)
- Julien Mancini (113512)
- Catherine Farnarier (113514)
- Céline Cognet (113515)
- Christophe Guervilly (113517)
- Aurélie Daumas (113519)
- Frédéric Vély (113521)
- François Xéridat (113523)
- Eric Vivier (48284)
- Laurent Papazian (64990)
Publication date
December 2012
DOIAbstract
<p>Correlation between the direct cytotoxicity CFSE-based assay and the degranulation CD107a expression assay to evaluate cytotoxic functions of NK cells in ICU patients (<i>n</i> = 14). Results are expressed as % lysis of target cell for the CFSE-assay, and as % NK-cell expressing CD107a for the degranulation assay. Effector–target ratio is 50/1 (PBMC/K562) for the CFSE-assay, and 2.5/1 (NK/K562) for the CD107a expression assay.</p
Add to ORKG