Protection of macaques against vaginal SHIV challenge by pretreatment with M48U1 gel.

<p>Viral loads in placebo (<b>A</b>) and M48U1-gel (<b>B</b>) treated macaques. One hour after gel application, animals were challenged with 10 AID₅₀ of SHIV_162P3. Macaques were monitored regularly for plasma viremia for 78 days. The area below the ordinate axis break represents values below the 60 RNA copies/mL detection limit (BD – below detection).