T cells recruited to the lung airways express CXCR3.

<p>Expression of CXCR3 on T lymphocytes of lung airway cells obtained from the BAL fluid of wt balb/c mice was compared on days one and four following IN administration of pIC. IN administration of PBS served as a control. (A) Representative FACS plots show the frequency of CD44 and CXCR3 expression on CD3⁺CD4⁺ (upper panels) or CD3⁺CD8⁺ (lower panels) gated lung airway cells. (B) Absolute numbers of CD44⁺CXCR3⁺ T lymphocytes present in the CD3⁺CD4⁺ (dark grey bars) and CD3⁺CD8⁺ (light grey bars) populations. The data are representative from two independent experiments with 3 mice/group. Error bars represent standard deviation.