<p>Values are expressed as mean ± SD.</p><p>°p<0.01 ZDF 2 months vs. LEAN 2 months;</p><p>°°p<0.01 ZDF 2 months vs. LEAN 2 months;</p>*<p>p<0.01;</p>**<p>p<0.001 ZDF 8 months vs. LEAN 8 months;</p>Δ<p>p<0.001 ZDF 8months vs. ZDF 2months;</p>$<p>p<0.001 LEAN 8months vs. LEAN 2 months.</p
<p>For biomarker definition urine samples of ZDF and LEAN control rats were used. The defined ZDF ra...
This study investigated the temporal relationship between cardiomyopathy and renal pathology in the ...
Aims/hypothesis: The aim of this study was to investigate the effects of a secondary renal insult, d...
<p>Values are mean ± SEM or median (IQR). *<i>p</i><0.05, **<i>p</i><0.01 vs lean; <sup>#</sup><i>p<...
<p>A) Photomicrographs showing representative sections of kidneys from LEAN and ZDF rats at 2 and 8 ...
<p>Abbreviations: HR, heart rate; bpm, beats per minute; SBP, systolic blood pressure; MDA, malondia...
<p>Compared with the 3-month-old group;</p><p>* indicates P<0.05; compared with the 12-month-old gro...
<p>(A) Shown are representative sections for lean control rats (top left) and untreated ZDF rats (to...
<p>The worsening of renal function associated with the <sup>cp/cp</sup> genotype was evaluated while...
<p>(A) Serum total cholesterol, (B) serum triglycerides, (C) serum blood urea nitrogen (BUN), (D) ur...
<p>Serum parameters were measured under fed condition. Urinary parameters were measured after the co...
<p>ZDF rats were hyperglycemic in the fed state at 8 and 10 weeks of age, but measurements were high...
<p>Abbreviations: <i>n</i>, number of rats; P<sub>Cr</sub>, plasma creatinine; BUN, blood urea nitro...
<p>Values are mean ± SEM. SBP: systolic blood pressure. NS: normal salt diet. LS: low salt diet. HS:...
<p>Data were obtained from the metabolic cage study (collected over a 24 h period on Days 7 and 42)....
<p>For biomarker definition urine samples of ZDF and LEAN control rats were used. The defined ZDF ra...
This study investigated the temporal relationship between cardiomyopathy and renal pathology in the ...
Aims/hypothesis: The aim of this study was to investigate the effects of a secondary renal insult, d...
<p>Values are mean ± SEM or median (IQR). *<i>p</i><0.05, **<i>p</i><0.01 vs lean; <sup>#</sup><i>p<...
<p>A) Photomicrographs showing representative sections of kidneys from LEAN and ZDF rats at 2 and 8 ...
<p>Abbreviations: HR, heart rate; bpm, beats per minute; SBP, systolic blood pressure; MDA, malondia...
<p>Compared with the 3-month-old group;</p><p>* indicates P<0.05; compared with the 12-month-old gro...
<p>(A) Shown are representative sections for lean control rats (top left) and untreated ZDF rats (to...
<p>The worsening of renal function associated with the <sup>cp/cp</sup> genotype was evaluated while...
<p>(A) Serum total cholesterol, (B) serum triglycerides, (C) serum blood urea nitrogen (BUN), (D) ur...
<p>Serum parameters were measured under fed condition. Urinary parameters were measured after the co...
<p>ZDF rats were hyperglycemic in the fed state at 8 and 10 weeks of age, but measurements were high...
<p>Abbreviations: <i>n</i>, number of rats; P<sub>Cr</sub>, plasma creatinine; BUN, blood urea nitro...
<p>Values are mean ± SEM. SBP: systolic blood pressure. NS: normal salt diet. LS: low salt diet. HS:...
<p>Data were obtained from the metabolic cage study (collected over a 24 h period on Days 7 and 42)....
<p>For biomarker definition urine samples of ZDF and LEAN control rats were used. The defined ZDF ra...
This study investigated the temporal relationship between cardiomyopathy and renal pathology in the ...
Aims/hypothesis: The aim of this study was to investigate the effects of a secondary renal insult, d...