Functional crytopleurine analogs inhibited cyclin D1 expression.

<p>HepG2 cells were treated with crytopleurine analogs and DCB-3503 with the dosage as indicated in the figure for 2 and 4 hours. Cyclin D1 protein level was analyzed by Western blot. The band intensity of Cyclin D1 on Western blot was normalized with that of β-actin by densitometer scanning, and presented as a chart below. Results were mean ± SD from three independent experiments.