Validation of EZH2 protein expression by quantitative image analysis of whole tissue sections.

<p>A: Proportion of EZH2 expressing tumor cells in paired lymph node and primary tumor sections are presented as adjacent bars. Percentage of EZH2+ tumor cells among the total number of tumor cells are indicated by Y axis. B: Correlation between percentage of EZH2 expressing tumor cells and percentage of proliferating cells. Lymph node metastases are indicated by solid circle and primary tumors by open circle. The Pearson correlation coefficient is 0.74 with p-value 0.001.