<p>The left panel depicts the Eigenvalues of the correspondence analysis and shows that the major factors contributing to the variance of stroketomics analysis were stroke (52%), post-stroke time (25%) and age (12%). (Right panel): The first two sources of variability, stroke and post-stroke time formed the coordinates of the right panel. The graph shows the distribution of transcripts (black dotes) as a function of treatment (stroke) and post-stroke time. Samples from young (green) and aged (red) animals particularly differ in their post-stroke response (illustrated by ellipses that form non-parallel planes). Transcripts with characteristic expression in naive samples are encircled in black.</p
BACKGROUND: A large number of genes are regulated to promote brain repair following stroke. The thor...
Whole genome expression microarrays can be used to study gene expression in blood, which comes in pa...
<p>A) Box and Whisker plot showing non-synonymous to synonymous substitution ratios () for genes in ...
<p>There were several distinct patterns of gene regulation: persistently upregulated (black line), t...
A) Direct comparison of the up and downregulated genes for the ischemic stroke and the Sham groups a...
<p>Note that at 14 days post-stroke, the differences between the age groups were more pronounced.</p
<p>Scaled expression values of all 1,658 differentially expressed genes are shown for each group wit...
<p>Graphical representation of significant gene-specific changes (fold-change: ratio test/common ref...
Stroke patients are often left with permanent disabilities with no regenerative treatment options. U...
Stroke is the most common cause of long-term disability, and there are no known drug therapies to im...
<p>The MA plots show the correlation of the hybridization signal intensity for the expressed genes c...
Genes identified by Tang et al. and their expression in our time course data. Results presented as a...
Stroke evolution is a highly dynamic but variable disease which makes clinical decision making diffi...
Background: A large number of genes are regulated to promote brain repair following stroke. The thor...
Genes identified by Tang et al. and their expression in our time course data. Results presented as a...
BACKGROUND: A large number of genes are regulated to promote brain repair following stroke. The thor...
Whole genome expression microarrays can be used to study gene expression in blood, which comes in pa...
<p>A) Box and Whisker plot showing non-synonymous to synonymous substitution ratios () for genes in ...
<p>There were several distinct patterns of gene regulation: persistently upregulated (black line), t...
A) Direct comparison of the up and downregulated genes for the ischemic stroke and the Sham groups a...
<p>Note that at 14 days post-stroke, the differences between the age groups were more pronounced.</p
<p>Scaled expression values of all 1,658 differentially expressed genes are shown for each group wit...
<p>Graphical representation of significant gene-specific changes (fold-change: ratio test/common ref...
Stroke patients are often left with permanent disabilities with no regenerative treatment options. U...
Stroke is the most common cause of long-term disability, and there are no known drug therapies to im...
<p>The MA plots show the correlation of the hybridization signal intensity for the expressed genes c...
Genes identified by Tang et al. and their expression in our time course data. Results presented as a...
Stroke evolution is a highly dynamic but variable disease which makes clinical decision making diffi...
Background: A large number of genes are regulated to promote brain repair following stroke. The thor...
Genes identified by Tang et al. and their expression in our time course data. Results presented as a...
BACKGROUND: A large number of genes are regulated to promote brain repair following stroke. The thor...
Whole genome expression microarrays can be used to study gene expression in blood, which comes in pa...
<p>A) Box and Whisker plot showing non-synonymous to synonymous substitution ratios () for genes in ...