Gene expression for several new potential therapeutic targets to improve post-stroke recovery in aged animals.

<p>Legend</p><p>↔ no changes vs contralateral side.</p><p>↑ upregulated vs contralateral side.</p><p>↓ downregulated vs contralateral side.</p><p>y/3d Young, 3d post-stroke.</p><p>y/14d Young, 14d post-stroke.</p><p>A/3d Aged, 3d post-stroke.</p><p>A/14d Aged, 14d post-stroke.</p><p>Confirmation of arrays data for new stroke-related genes was done by RT-PCR. Modulation of gene/protein activity by the indicated drugs may, in combination or alone, improve post-stroke recovery in aged animals. For most of the upregulated genes there is a therapeutic option but not for downregulated genes.