The baseline colonic expression of cytokines and IL-10 receptor subunits is developmentally regulated prior to weaning.

<p>Cytokine and IL-10 receptor subunit expression was analyzed by real time PCR in whole colon from 1, 2 and 3 week-old C57BL/6J mice. The data represent mean fold change ± SEM, relative to 1 week-old mice (A, B). C. IL-10 cytokine levels in supernatants of whole colon incubated for 24 hours were assayed by ELISA and depicted as mean concentration ± SEM (*p<0.05, n = 5−7 mice per age group).