MPSSS inhibited tumor growth and reduced MDSC numbers.

<p>(A) C57BL/6 mice were injected subcutaneously with 1×10⁶ McgR32 cellsand 8 day later, with MPSSS or PBS intraperitoneally once every two days. Tumor volume was recorded as the mean ± SD and each group contained 3–4 mice and was analyzed by one-way ANOVA for repeated measures data. (B) At the indicated days after tumor cell injection, peripheral blood was taken for MDSC detection by flow cytometry, Quantitative data are expressed as mean ± SD and analyzed by Student's <i>t</i> tests. *<i>P</i><0.05, **<i>P</i><0.01. (C) A representative flow cytometry analysis was shown for the staining of CD11b and Gr1.