<p>The horizontal axis shows the intervals of each stimulation. The vertical axis shows the ratio of increase of synapses at two weeks after the first stimulation. The colored lines show the synaptic maintenance response with various <i>delays</i>. Red line: 0 min (no delay); Green line: 30 min; Blue line: 60 min; Purple line: 120 min. The two vertical dotted lines show the approximate upper limit and lower limit of intervals between three times stimuli for synaptic maintenance in experimental results <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0051000#pone.0051000-Yamamoto1" target="_blank">[20]</a>.</p
<p>L-LTP – inducing tetani (simulated as in <a href="http://www.plosone.org/article/info:doi/10.1371...
<p>The graphs (A-D) show the <i>β</i>-Power, root mean square value of the activity and power spectr...
We develop a minimal time-continuous model for use-dependent synap-tic short-term plasticity that ca...
<p>Each graph shows the response of synaptic maintenance to a fluctuation in a set of labeled parame...
<p>Each graph shows the response of synaptic maintenance to a fluctuation in a labeled parameter. Th...
<p>A, B and C: synaptic maintenance occurs when stimulation exceeds the threshold. Repetitive stimul...
<p>A: A simulation result of our mathematical model with a single stimulation. The red dots show tim...
<p>(<b>A</b>) Temporal evolution of the average firing rate in the excitatory population for differe...
The mechanisms of long-term synaptic maintenance are a key component to understanding the mechanism ...
<p><b>A–C</b>: The effect of the continuous-time plasticity rule in <a href="http://www.ploscompbiol...
KEY WORDS LTP; LTD; hippocampus; minimal stimulation; binary synapses ABSTRACT At individual synapse...
<p>Upper Figure: 0–5000 min, Lower Figure: 0–20160 min (14 days) The colored lines show the time-cou...
The mechanisms of long-term synaptic maintenance are a key component to understanding the mechanism ...
Experimental studies have observed synaptic potentiation when a presynaptic neuron fires shortly bef...
Experimental studies have observed synaptic potentiation when a presynaptic neuron fires shortly bef...
<p>L-LTP – inducing tetani (simulated as in <a href="http://www.plosone.org/article/info:doi/10.1371...
<p>The graphs (A-D) show the <i>β</i>-Power, root mean square value of the activity and power spectr...
We develop a minimal time-continuous model for use-dependent synap-tic short-term plasticity that ca...
<p>Each graph shows the response of synaptic maintenance to a fluctuation in a set of labeled parame...
<p>Each graph shows the response of synaptic maintenance to a fluctuation in a labeled parameter. Th...
<p>A, B and C: synaptic maintenance occurs when stimulation exceeds the threshold. Repetitive stimul...
<p>A: A simulation result of our mathematical model with a single stimulation. The red dots show tim...
<p>(<b>A</b>) Temporal evolution of the average firing rate in the excitatory population for differe...
The mechanisms of long-term synaptic maintenance are a key component to understanding the mechanism ...
<p><b>A–C</b>: The effect of the continuous-time plasticity rule in <a href="http://www.ploscompbiol...
KEY WORDS LTP; LTD; hippocampus; minimal stimulation; binary synapses ABSTRACT At individual synapse...
<p>Upper Figure: 0–5000 min, Lower Figure: 0–20160 min (14 days) The colored lines show the time-cou...
The mechanisms of long-term synaptic maintenance are a key component to understanding the mechanism ...
Experimental studies have observed synaptic potentiation when a presynaptic neuron fires shortly bef...
Experimental studies have observed synaptic potentiation when a presynaptic neuron fires shortly bef...
<p>L-LTP – inducing tetani (simulated as in <a href="http://www.plosone.org/article/info:doi/10.1371...
<p>The graphs (A-D) show the <i>β</i>-Power, root mean square value of the activity and power spectr...
We develop a minimal time-continuous model for use-dependent synap-tic short-term plasticity that ca...