Dasatinib inhibits cell adhesion to integrin ligand GLOGER but not to DDR ligand GVMGFO.

<p>293-DDR cells or empty-vector control cells (293-EV) were allowed to adhere to the integrin-specific peptide GLOGER (A) or to the DDR-specific peptide GPRGQOGVNleGFO (GVMGFO) (B) for 1 h at 37°C in the presence or absence of dasatinib at the indicated concentrations. The data are the means ± SEM of 3–5 independent experiments, each performed in triplicate. Due to variability of cell adhesion to GVMGFO, the data are normalised to adhesion in the absence of dasatinib, which was set to 100%.