Validation of microarray results using MALDI-TOF mass spectrometry (MassARRAY).

<p>CtDMRs are labeled by the gene symbol of the closest gene. Each ctDMR is shown as a heatmap; methylation level for each informative CpG fragment is shown in columns and analyzed samples are organized in rows. Each colored rectangle corresponds to 1 CpG unit. All three genotypes were analyzed. White spaces are shown when the quality of data was not sufficient to assess methylation. <b>A</b>) ctDMRs which are methylated in HMF according to microarray. <b>B)</b> ctDMRs which are methylated in HMEC according to microarray. A more detailed view for each analyzed region is included in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0052299#pone.0052299.s003" target="_blank">Information S1</a>.