Neural activity for main effect of group (A) and condition (B).

<p>Neural activity for (A) main effect of group, which yields stronger activation in the auditory cortex (AC), inferior frontal gyrus (Broca’s area) and anterior cingulate cortex (ACC)/left medial frontal gyrus for the L-dopa treated group compared to the placebo group. (B) Main effect of condition which shows stronger activation for rewarded (CS+) compared to non-rewarded tones (CS−), in several dopaminergic brain areas, such as nucleus accumbens (NAC) and midbrain regions (SN/VTA), as well as insula.