Angiotensin II (AT-II) attenuates GCDCA-induced ER stress in rat hepatocytes.

<p>(<b>A</b>) QPCR analysis of Chop mRNA (ER stress marker) in rat hepatocytes treated with 50 µmol/L GCDCA at several time points with or without 100 nmol/L of AT-II using cDNA of hepatocytes. mRNA expression level is presented relative to control. One-way ANOVA test was used to determine the significance of differences between experimental groups (N = 3).* P<0.05 for GCDCA +AT-II vs. GCDCA alone at 2 hours.