Induction of DNA repair genes at the exon level four hours after treatment with 10 Gy IR in LCLs.

<p>The top five DNA repair genes: <i>XPC</i> (A), <i>POLH</i> (B), <i>DDB2</i> (C), <i>PCNA</i> (D) and <i>RRM2B</i> (E) as identified using Partek Genomics Suite 6.6 statistical package. Relative fluorescence (y-axis; log₂) is plotted for each PSR (x-axis). Core PSRs are labelled numerically in a 5′ to 3′ direction (left to right). Samples were either sham irradiated (red) or irradiated (blue) with 10 Gy from a ¹³⁷Cs source. Arrow indicates the PSR region to which primers were designed for qRT-PCR used in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0053358#pone-0053358-g003" target="_blank">figure 3A</a>. Error bars = SEM (n = 12).