Nuclear and cellular remodeling accompany T-cell activation.

<p>a) Representative time-lapse images of T-cells during activation. Green- H2B EGFP nucleus; black- antigen-coated beads. Scale bar 5 µm. b) Schematic representation of experimental design. c) XY trajectory of the centroid of a bead and cell nucleus in M− and M+ conditions. d) Distance between the centroids of a bead and a cell nucleus in M− and M+ conditions.