Effect of a sub-chronic treatment with IRC-082451 on locomotor activity.
- Romina Aron Badin (105277)
- Brigitte Spinnewyn (105280)
- Marie-Claude Gaillard (46536)
- Caroline Jan (105282)
- Carole Malgorn (46535)
- Nadja Van Camp (105284)
- Frédéric Dollé (105287)
- Martine Guillermier (105289)
- Sabrina Boulet (105291)
- Anne Bertrand (105293)
- Marc Savasta (105295)
- Michel Auguet (105297)
- Emmanuel Brouillet (46542)
- Pierre-Etienne Chabrier (105302)
- Philippe Hantraye (46540)
Publication date
January 2013
DOIAbstract
<p>The 5-day sub-chronic treatment with 5 mg/kg IRC was given concomitantly with L-DOPA and the total number of dyskinesias and distance travelled on day 5 are presented. A significant reduction in LID count was observed (A) together with an increase in spontaneous TDT (B) compared to the same animals under vehicle treatment. Data are presented as mean ± s.e.m. Unpaired Student <i>t</i> test (**, p<0.01).</p
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